Pneumoconiosis: current status and future prospects

被引：73

作者：

Qi, Xian-Mei ^{[1
]}

Luo, Ya ^{[1
]}

Song, Mei-Yue ^{[2
]}

Liu, Ying ^{[1
,3
]}

Shu, Ting ^{[1
]}

Pang, Jun-Ling ^{[1
]}

Wang, Jing ^{[1
]}

Wang, Chen ^{[3
]}

机构：

[1] Chinese Acad Med Sci, Peking Union Med Coll, Inst Basic Med Sci, Dept Pathophysiol,State Key Lab Med Mol Biol, Beijing 100730, Peoples R China

[2] Beijing Univ Chinese Med, Beijing 100029, Peoples R China

[3] Chinese Acad Med Sci, Peking Union Med Coll, Inst Basic Med Sci, Dept Physiol,State Key Lab Med Mol Biol, Beijing 100730, Peoples R China

来源：

CHINESE MEDICAL JOURNAL | 2021年 / 134卷 / 08期

关键词：

Pneumoconiosis; Epidemiology; Diagnosis; Treatment; Emerging technologies; INTERSTITIAL LUNG-DISEASE; STEM-CELLS; MESENCHYMAL TRANSITION; PULMONARY INFLAMMATION; INDUCED SILICOSIS; COAL-WORKERS; RAT MODEL; FIBROSIS; PIRFENIDONE; TRANSPLANTATION;

D O I：

10.1097/CM9.0000000000001461

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Pneumoconiosis refers to a spectrum of pulmonary diseases caused by inhalation of mineral dust, usually as the result of certain occupations. The main pathological features include chronic pulmonary inflammation and progressive pulmonary fibrosis, which can eventually lead to death caused by respiratory and/or heart failure. Pneumoconiosis is widespread globally, seriously threatening global public health. Its high incidence and mortality lie in improper occupational protection, and in the lack of early diagnostic methods and effective treatments. This article reviews the epidemiology, safeguard procedures, diagnosis, and treatment of pneumoconiosis, and summarizes recent research advances and future research prospects.

引用

页码：898 / 907

页数：10

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