Serum adenosine deaminase activity in gestational diabetes mellitus and normal pregnancy

被引：19
|
作者：
Mokhtari, Mojgan [2 ]
Hashemi, Mohammad [1 ,3 ]
Yaghmaei, Minoo [2 ]
Molashahi, Fariba [2 ]
Shikhzadeh, Abdolsamad [2 ]
Niazi, Abbasali [4 ]
Ghavami, Saeid [5 ]
机构：
[1] Zahedan Univ Med Sci, Sch Med, Dept Clin Biochem, Zahedan, Iran
[2] Zahedan Univ Med Sci, Sch Med, Dept Obstet & Gynaecol, Zahedan, Iran
[3] Zahedan Univ Med Sci, Celluar & Mol Res Ctr, Zahedan, Iran
[4] Zahedan Univ Med Sci, Sch Med, Dept Pathol, Zahedan, Iran
[5] Univ Manitoba, Dept Physiol, Manitoba Inst Child Hlth, Winnipeg, MB, Canada
来源：
ARCHIVES OF GYNECOLOGY AND OBSTETRICS | 2010年 / 281卷 / 04期
关键词：
Adenosine deaminase; Gestational diabetes mellitus; Pregnancy; INSULIN; SYSTEM; WOMEN; PREECLAMPSIA; ADIPOCYTES; ACID; TH1;
D O I：
10.1007/s00404-009-1148-3
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
To our knowledge, there is no report regarding adenosine deaminase activity (ADA) in gestational diabetes mellitus (GDM). The aim of the present study was to investigate the level of serum ADA activity in normal pregnancy, GDM and normal non-pregnant women. The serum catalytic concentration of ADA was measured in samples of 20 GDM, 40 normal pregnant and 20 non-pregnant healthy women. Adenosine deaminase activity was significantly higher in GDM (24.30 +/- A 8.04 IU/L) and pregnant women (23.88 +/- A 8.66 IU/L) than those of normal non-pregnant individuals (11.85 +/- A 3.23 IU/L) (P < 0.0001), but the ADA level was not significantly different from GDM and normal pregnant women (P = 0.97). Adenosine deaminase activity was significantly higher in GDM and pregnant individuals than normal group in this study. Previous reports in this field are contentious; therefore, ADA activity could be regulated in different population by immunologic and genetic factors.
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收藏
页码：623 / 626
页数：4
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