Delayed Hemolytic Transfusion Reaction in Sickle Cell Disease

被引:45
|
作者
Scheunemann, Leslie P. [1 ]
Ataga, Kenneth I. [1 ]
机构
[1] Univ N Carolina, Dept Med, Div Hematol Oncol, Chapel Hill, NC 27599 USA
来源
关键词
Sickle cell disease; Transfusion reaction; Delayed hemolytic transfusion reaction; ALLOIMMUNIZATION; ANEMIA; BLOOD; INFLAMMATION; PATIENT; DEATH; RISK;
D O I
10.1097/MAJ.0b013e3181c70e14
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Delayed hemolytic transfusion reactions are potentially life-threatening complications observed in patients with sickle cell disease. We review the clinical features, pathophysiology, laboratory evaluation, and management of this complication. It is important that delayed hemolytic transfusion reactions be included in the differential diagnosis of acute pain episodes following a red blood cell transfusion in a patient with sickle cell disease.
引用
收藏
页码:266 / 269
页数:4
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