Semantic category discrimination and N400

14 subjects performed a semantic category-discrimination task in which they were presented pairs of words and asked to judge whether these belonged to the same category. Three semantic distance conditions, established for the word pairs on the basis of a survey, were semantically close condition (mammals and birds condition) and two semantically distant conditions (mammals and tools condition and birds and tools condition). The reaction times and the percentage of errors were significantly greatest for the mammals and bird condition. There were no significant differences among the three different conditions in N400 latency for target, bur the amplitude of N400 tended to be largest for the mammal and bird condition. Comparison N400 of prime and target for each of the conditions showed that the latency for prime was longer than for target in all three conditions.