CAG repeat length of the androgen receptor gene in Japanese males with cryptorchidism

被引：34
|
作者：
Sasagawa, I
Suzuki, Y
Tateno, T
Nakada, T
Muroya, K
Ogata, T
机构：
[1] Yamagata Univ, Sch Med, Dept Urol, Yamagata 9909585, Japan
[2] Keio Univ, Sch Med, Dept Pediat, Tokyo, Japan
来源：
MOLECULAR HUMAN REPRODUCTION | 2000年 / 6卷 / 11期
关键词：
androgen receptor; CAG repeat; cryptorchidism;
D O I：
10.1093/molehr/6.11.973
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
We have analysed the CAG repeat length in exon 1 of the androgen receptor gene in 48 Japanese males with cryptorchidism and 100 fertile Japanese males. The CAG repeat length was 23.4 +/- 0.48 (mean +/- SE) (range 16-32, median 23) in cryptorchid patients and 23.5 +/- 0.29 (range 15-32, median 23) in normal males. There was no significant difference between the two groups. The expansion of the CAG repeats in axon 1 of the androgen receptor gene is unlikely to constitute a major cause of cryptorchidism.
引用
收藏
页码：973 / 975
页数：3
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