Current Challenges of Cardiac Amyloidosis Awareness among Romanian Cardiologists

被引:5
|
作者
Adam, Robert [1 ,2 ,4 ,5 ]
Neculae, Gabriela [1 ]
Stan, Claudiu [2 ,3 ]
Jurcut, Ruxandra [1 ,2 ]
机构
[1] Prof Dr CC Iliescu Emergency Inst Cardiovasc Dis, Expert Ctr Rare Genet Cardiovasc Dis, Dept Cardiol, Bucharest 022328, Romania
[2] Carol Davila Univ Med & Pharm, Bucharest 030167, Romania
[3] Fundeni Clin Inst, Dept Nucl Med & Ultrasonog, Bucharest 022328, Romania
[4] Prof Dr CC Iliescu Emergency Inst Cardiovasc Dis, Bucharest 022328, Romania
[5] 3rd Cardiol Dept, 258 Fundeni St, Bucharest 022328, Romania
关键词
amyloidosis; cardiologist; awareness; survey; ATTR; AORTIC-STENOSIS; TRANSTHYRETIN AMYLOIDOSIS; NATURAL-HISTORY; AL AMYLOIDOSIS; HEART-FAILURE; DIAGNOSIS; PREVALENCE; SYMPTOM;
D O I
10.3390/diagnostics11050834
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Cardiac amyloidosis (CA) is a restrictive cardiomyopathy characterized by deposition of amyloid in the myocardium and recent studies revealed it is more frequently seen than we thought. Advances in diagnosis and treatment have been made over the last few years that make it desirable to diagnose CA without delay, and that may require extra education. An online survey was conducted among cardiologists from Romania, representing the first assessment of the knowledge of CA among them, with 195 cardiologists answering the questionnaire. There was a wide variation in their knowledge regarding CA. Our participants had limited experience with CA and reported a significant delay between first cardiac symptoms and diagnosis. We address the gaps in knowledge that were identified as educational opportunities in the main identified areas: prevalence and treatment of wild type transthyretin amyloidosis (ATTRwt), prevalence of variant transthyretin amyloidosis (ATTRv) in Romania, diagnosis of CA, the delay in CA diagnosis and available treatment options. Awareness among cardiologists is the most important challenge in diagnosing CA. Romanian cardiologists are partially aware of this topic, but there are still gaps in their knowledge. Educational programs can improve screening of patients with a high suspicion for this progressive condition the prognosis of which has been dramatically changed by the new treatment options.
引用
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页数:12
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