Effects of Intermittent Fasting on Health, Aging, and Disease

被引:822
|
作者
de Cabo, Rafael [1 ]
Mattson, Mark P. [2 ,3 ]
机构
[1] NIA, Translat Gerontol Branch, NIH, Intramural Res Program, Baltimore, MD 21224 USA
[2] NIA, Neurosci Lab, NIH, Intramural Res Program, Baltimore, MD 21224 USA
[3] Johns Hopkins Univ, Sch Med, Dept Neurosci, 725 N Wolfe St, Baltimore, MD 21205 USA
来源
NEW ENGLAND JOURNAL OF MEDICINE | 2019年 / 381卷 / 26期
基金
美国国家卫生研究院;
关键词
INDUCED WEIGHT-LOSS; LOW-CALORIE DIET; ENERGY RESTRICTION; OXIDATIVE STRESS; MOLECULAR-MECHANISMS; RISK MARKERS; LIFE; INDIVIDUALS; METABOLISM; RESISTANCE;
D O I
10.1056/NEJMra1905136
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Evidence is accumulating that eating in a 6-hour period and fasting for 18 hours can trigger a metabolic switch from glucose-based to ketone-based energy, with increased stress resistance, increased longevity, and a decreased incidence of diseases, including cancer and obesity.
引用
收藏
页码:2541 / 2551
页数:11
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