Brain volumes in Guam dementia vs Parkinson dementia complex vs aging Chamorro adults

被引：0
|
作者：
Kaye, J. A.
Moore, M. M.
Galasko, D.
Craig, U. K.
Adonay, R.
Silbert, L. C.
机构：
[1] Oregon Hlth & Sci Univ, Layton Aging & Alzheimers Dis Ctr, Dept Neurol, Portland, OR 97239 USA
[2] Univ Calif San Diego, San Diego, CA 92103 USA
[3] Univ Guam, Mangilao, GU USA
来源：
NEUROLOGY | 2007年 / 69卷 / 02期
关键词：
D O I：
10.1212/01.wnl.0000265590.66637.e8
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
We sought to determine if Chamorro individuals with a family history of Guam dementia (GD) or Parkinson dementia complex (PDC) exhibit presymptomatic brain MRI changes. Sixty-six Chamorro subjects had neurocognitive assessment and volumetric MRI. MRI brain volumes differed between diagnostic groups (GD, PDC, control) and according to family history. Chamorros with a family history of PDC or dementia may have increased brain atrophy, suggesting a hereditary susceptibility to neurodegenerative disorders.
引用
收藏
页码：196 / 199
页数：4
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