Non-pharmacological and pharmacological Therapy of Delirium

被引：2

作者：

Reith, Sebastian ^{[1
,2
,3
,4
,5
]}

机构：

[1] Unikliniken Aachen, Innere Med Kardiol Internist Intens Med & Notfa, Aachen, Germany

[2] Klinikum Krefeld, Krefeld, Germany

[3] St Antonius Hosp Eschweiler, Eschweiler, Germany

[4] Uniklinikum Aachen, Med Klin 1, Aachen, Germany

[5] St Franziskus Hosp Munster, Med Klin 3, Hohenzollernring 70, D-48145 Munster, Germany

来源：

DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT | 2019年 / 144卷 / 23期

关键词：

CRITICALLY-ILL PATIENTS; PREVENT DELIRIUM; HALOPERIDOL PROPHYLAXIS; DEXMEDETOMIDINE; INTERVENTION; MANAGEMENT; SEDATION; EFFICACY; MIDAZOLAM; SURGERY;

D O I：

10.1055/a-0826-2780

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The therapeutic management of delirium is based on two major columns. The cornerstone of therapy is the non-pharmacological intervention using a multifactorial approach including early mobilization, reorientation, improvement of cerebral and cognitive activity and the consequent establishment of adequate wake-/sleep cycles. Evidence for specific pharmacotherapy in delirium is currently rare, for both delirium prophylaxis as well as for definitive therapy of clinically apparent delirium. However, in clinical routine several substances are commonly used for the management of delirium particularly in a symptom-oriented choice. Moreover, regarding delirium prophylaxis the choice of sedativum has an important clinical impact on the incidence of delirium. © 2019 Georg Thieme Verlag. All rights reserved.

引用

页码：1629 / 1635

页数：7

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