Work-Related Asthma: Diagnosis and Prognosis of Immunological Occupational Asthma and Work-Exacerbated Asthma

被引：0

作者：

Munoz, X. ^{[1
,2
,3
]}

Cruz, M. J. ^{[1
,2
]}

Bustamante, V. ^{[4
]}

Lopez-Campos, J. L. ^{[2
,5
]}

Barreiro, E. ^{[2
,6
]}

机构：

[1] Univ Autonoma Barcelona, Hosp Univ Vall Hebron, Dept Med, Pulmonol Serv, E-08193 Barcelona, Spain

[2] Ctr Invest Red Enfermedades Resp CIBERES, Inst Salud Carlos III, Madrid, Spain

[3] Univ Autonoma Barcelona, Dept Cell Biol Physiol & Immunol, E-08193 Barcelona, Spain

[4] Osakidetza Univ Basque Country,Spain, Hosp Univ Basurto, Dept Pneumol, Bilbao, Spain

[5] Univ Seville, Hosp Univ Virgen Rocio, Inst Biomed Sevilla IBIS, Unidad Medicoquirurg Enfermedades Resp, Seville, Spain

[6] Univ Pompeu Fabra, Inst Hosp Mar Invest Mediques IMIM, Muscle Res & Resp Syst Unit URMAR,Hosp Mar, Dept Expt & Hlth Sci CEXS,Dept Pulmonol,PRBB, Barcelona, Spain

来源：

JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY | 2014年 / 24卷 / 06期

关键词：

Specific inhalation challenge; Peak expiratory flow; Workplace; Irritants; PEAK EXPIRATORY FLOW; EXHALED BREATH CONDENSATE; NONSPECIFIC BRONCHIAL HYPERRESPONSIVENESS; THORACIC-SOCIETY STATEMENT; NEW-ONSET ASTHMA; INHALATION CHALLENGE; NITRIC-OXIDE; FOLLOW-UP; AIRWAY INFLAMMATION; NONINVASIVE METHODS;

D O I：

暂无

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

The incidence and prevalence of asthma are increasing. One reason for this trend is the rise in adult-onset asthma, especially occupational asthma, which is 1 of the 2 forms of work-related asthma. Occupational asthma is defined as asthma caused by agents that are present exclusively in the workplace. The presence of pre-existing asthma does not rule out the possibility of developing occupational asthma. A distinction has traditionally been made between immunological occupational asthma (whether IgE-mediated or not) and nonimmunological occupational asthma caused by irritants, the most characteristic example of which is reactive airway dysfunction syndrome. The other form of work-related asthma is known as work-exacerbated asthma, which affects persons with pre-existing or concurrent asthma that is worsened by work-related factors. It is important to differentiate between the 2 entities because their treatment, prognosis, and medical and social repercussions can differ widely. In this review, we discuss diagnostic methods, treatment, and avoidance/nonavoidance of the antigen in immunological occupational asthma and work-exacerbated asthma.

引用

页码：396 / 405

页数：10

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