The Long-Term Course of Atopic Dermatitis

被引:51
|
作者
Abuabara, Katrina [1 ]
Margolis, David J. [2 ]
Langan, Sinead M. [3 ,4 ]
机构
[1] Univ Calif San Francisco, Dept Dermatol, 2340 Sutter St,N421, San Francisco, CA 94115 USA
[2] London Sch Hyg & Trop Med, Fac Epidemiol & Populat Hlth, Keppel St, London WC1E 7HT, England
[3] Univ Penn, Perelman Sch Med, Dept Dermatol, 3400 Civ Ctr Blvd, Philadelphia, PA 19104 USA
[4] Univ Penn, Perelman Sch Med, Dept Biostat & Epidemiol, 3400 Civ Ctr Blvd, Philadelphia, PA 19104 USA
基金
英国惠康基金;
关键词
Atopic dermatitis; Eczema; Atopic eczema; Epidemiology; Natural history; Clinical course; TRANSEPIDERMAL WATER-LOSS; BIRTH COHORT; SKIN BARRIER; CONTACT-DERMATITIS; ECZEMA PREVALENCE; NATURAL-HISTORY; CHILDREN; PERSISTENCE; ASTHMA; AGE;
D O I
10.1016/j.det.2017.02.003
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Atopic dermatitis (AD) is a chronic, relapsing condition, meaning that the intensity of symptoms usually fluctuates over time. Changes in skin physiology may be evident from birth, suggesting that AD may be a lifelong condition marked by intermittent symptoms/disease activity. Methodological considerations for studying the long-term course of AD are reviewed in detail. Improved measurement of the frequency and duration of active disease periods can help to elucidate more about the clinical course AD and the role of treatment in long-term outcomes.
引用
收藏
页码:291 / +
页数:8
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