Anti-angiogenesis drugs in lung cancer

被引：6

作者：

Lee, Siow Ming ^{[1
,2
,3
]}

Baas, Paul ^{[4
]}

Wakelee, Heather ^{[5
]}

机构：

[1] Univ Coll London Hosp, NHS Trust, London NW1 2PG, England

[2] UCL Canc Inst, London, England

[3] Univ Coll Hosp, Dept Oncol, London, England

[4] Netherlands Canc Inst, Dept Thorac Oncol, Amsterdam, Netherlands

[5] Stanford Univ, Dept Med, Stanford Canc Ctr, Div Oncol, Stanford, CA 94305 USA

来源：

RESPIROLOGY | 2010年 / 15卷 / 03期

关键词：

bevacizumab; lung cancer; VEGF; anti-angiogenesis; PHASE-III TRIAL; CISPLATIN PLUS GEMCITABINE; ENDOTHELIAL-CELLS; DOUBLE-BLIND; CHEMOTHERAPY; CARBOPLATIN; PACLITAXEL; COMBINATION; THERAPY; PLACEBO;

D O I：

10.1111/j.1440-1843.2010.01715.x

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

In the last years much attention has been given to the implementation of the so-called targeted drugs. One of the targets of tumours is the vasculature and this has led to the development of anti-angiogenic drugs. In lung cancer the use of these drugs has resulted in both positive and negative studies. In this paper the pros and cons are presented. We hope that this information will help the physician in making a proper treatment choice.

引用

页码：387 / 392

页数：6

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