Impact of an automatic hospital probiotic protocol on Clostridioides (Clostridium) difficile infection (CDI) rates and CDI antibiotic usage in a community hospital setting

被引:3
|
作者
Slain, Douglas [1 ]
Georgulis, Amy [2 ]
Dermitt, Ron [2 ]
Morris, Laura [3 ]
Colodny, Stephen M. [2 ]
机构
[1] West Virginia Univ, 1124 Hlth Sci North, Morgantown, WV 26506 USA
[2] St Clair Hosp, Pittsburgh, PA USA
[3] Special Pathogens Lab, Pittsburgh, PA USA
关键词
Clostridioides difficile; Clostridium difficile; probiotics; Saccharomyces boulardii;
D O I
10.1177/1757177419892309
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The aim of the present study was to see how widespread preventative use of the probiotic Saccharomyces boulardii via automatic protocol in hospitalised patients receiving antibacterials affected rates of hospital-associated Clostridioides (Clostridium) difficile infection (HA-CDI). Rates of HA-CDI appeared to be similar between the pre-protocol and protocol periods. Use of CDI treatment antibiotics (oral metronidazole and oral vancomycin) was also similar. Laboratory-confirmed isolation of S. boulardii from sterile body sites was identified in five patients during the protocol versus only one case in the pre-protocol years.
引用
收藏
页码:72 / 75
页数:4
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