Identification of an ancillary protein, YabF, required for activity of the KefC glutathione-gated potassium efflux system in Escherichia coli

被引：34

作者：

Miller, S ^{[1
]}

Ness, LS ^{[1
]}

Wood, CM ^{[1
]}

Fox, BC ^{[1
]}

Booth, IR ^{[1
]}

机构：

[1] Univ Aberdeen, Inst Med Sci, Dept Mol & Cell Biol, Aberdeen AB25 2ZD, Scotland

来源：

JOURNAL OF BACTERIOLOGY | 2000年 / 182卷 / 22期

基金：

英国惠康基金;

关键词：

D O I：

10.1128/JB.182.22.6536-6540.2000

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A new subunit, YabF, for the KefC K+ efflux system in Escherichia call has been identified. The subunit is required for maximum activity of KefC. Deletion of yabF reduces KefC activity 10-fold, and supply of YabF in trans restores activity. IS2 and IS10R insertions in yabF can be isolated as suppressors of KefC activity consequent upon the V427A and D264A KefC mutations.

引用

页码：6536 / 6540

页数：5

共 8 条

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Miller, S
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[2] Survival of Escherichia coli Cells Exposed to Iodoacetate and Chlorodinitrobenzene Is Independent of the Glutathione-Gated K+ Efflux Systems KefB and KefC
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Applied and Environmental Microbiology, 63 (10):
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Booth, IR
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1997, 63 (10) : 4083 - 4086
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APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2004, 70 (09) : 5569 - 5578
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