Constrained polarization evolution simplifies depth-resolved retardation measurements with polarization-sensitive optical coherence tomography

被引:10
|
作者
Xiong, Qiaozhou [1 ]
Wang, Nanshuo [1 ]
Liu, Xinyu [1 ,3 ]
Chen, Si [1 ]
Braganza, Cilwyn S. [1 ]
Bouma, Brett E. [4 ,5 ,6 ]
Liu, Linbo [1 ,2 ]
Villiger, Martin [4 ,5 ]
机构
[1] Nanyang Technol Univ, Sch Elect & Elect Engn, Singapore 639798, Singapore
[2] Nanyang Technol Univ, Sch Chem & Biomed Engn, Singapore 637459, Singapore
[3] Singapore Eye Res Inst, Singapore 169856, Singapore
[4] Harvard Med Sch, Boston, MA 02114 USA
[5] Massachusetts Gen Hosp, Wellman Ctr Photomed, Boston, MA 02114 USA
[6] MIT, Inst Med Engn & Sci, Cambridge, MA 02139 USA
基金
新加坡国家研究基金会; 美国国家卫生研究院;
关键词
NERVE-FIBER LAYER; MODE DISPERSION; AXIS ORIENTATION; BIREFRINGENCE; BACKSCATTERING; CONTRAST; SAMPLES; TISSUE;
D O I
10.1364/BOE.10.005207
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
We observed that the polarization state of light after round-trip propagation through a birefringent medium frequently aligns with the employed input polarization state 'mirrored' by the horizontal plane of the Poincare sphere. We explored the predisposition for this mirror state and evidence that it constrains the evolution of polarization states as a function of the round-trip depth into weakly scattering birefringent samples, as measured with polarization-sensitive optical coherence tomography (PS-OCT). Combined with spectral variations in the polarization state transmitted through system components, we demonstrate how this constraint enables measurement of depth-resolved birefringence using only a single input polarization state, which offers a critical simplification compared to conventional PS-OCT employing two input states. (C) 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreement
引用
收藏
页码:5207 / 5222
页数:16
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