Validation of the RayStation Monte Carlo dose calculation algorithm using realistic animal tissue phantoms

被引:25
|
作者
Schreuder, Andries N. [1 ]
Bridges, Daniel S. [1 ]
Rigsby, Lauren [1 ]
Blakey, Marc [1 ]
Janson, Martin [2 ]
Hedrick, Samantha G. [1 ]
Wilkinson, John B. [1 ]
机构
[1] Provis Ctr Proton Therapy Knoxville, Knoxville, TN 37909 USA
[2] PhDRaySearch Labs, Stockholm, Sweden
来源
关键词
analytical dose algorithms; Monte Carlo; pencil beam scanning; proton therapy; spot scanning; PENCIL BEAM ALGORITHM; CALCULATION ACCURACY; THERAPY;
D O I
10.1002/acm2.12733
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Purpose The aim of this study is to validate the RayStation Monte Carlo (MC) dose algorithm using animal tissue neck phantoms and a water breast phantom. Methods Three anthropomorphic phantoms were used in a clinical setting to test the RayStation MC dose algorithm. We used two real animal necks that were cut to a workable shape while frozen and then thawed before being CT scanned. Secondly, we made a patient breast phantom using a breast prosthesis filled with water and placed on a flat surface. Dose distributions in the animal and breast phantoms were measured using the MatriXX PT device. Results The measured doses to the neck and breast phantoms compared exceptionally well with doses calculated by the analytical pencil beam (APB) and MC algorithms. The comparisons between APB and MC dose calculations and MatriXX PT measurements yielded an average depth difference for best gamma agreement of <1 mm for the neck phantoms. For the breast phantom better average gamma pass rates between measured and calculated dose distributions were observed for the MC than for the APB algorithms. Conclusions The MC dose calculations are more accurate than the APB calculations for the static phantoms conditions we evaluated, especially in areas where significant inhomogeneous interfaces are traversed by the beam.
引用
收藏
页码:160 / 171
页数:12
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