Regulation of human osteoclast differentiation by thioredoxin binding protein-2 and redox-sensitive signaling

被引：37
|
作者：
Aitken, CJ
Hodge, JM
Nishinaka, Y
Vaughan, T
Yodoi, JJ
Day, CJ
Morrison, NA
Nicholson, GC [1 ]
机构：
[1] Univ Melbourne, Geelong Hosp, Dept Clin & Biomed Sci, Barwon Hlth, Geelong, Vic 3220, Australia
[2] Natl Inst Adv Ind Sci & Technol, Human Stress Signal Res Ctr, Biomed Special Res Unit, Osaka, Japan
[3] Griffith Univ, Sch Hlth Sci, Nathan, Qld 4111, Australia
来源：
JOURNAL OF BONE AND MINERAL RESEARCH | 2004年 / 19卷 / 12期
关键词：
osteoclast; thioredoxin binding protein-2; thioredoxin-1; redox; activator protein 1;
D O I：
10.1359/JBMR.040913
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Differential expression of TBP-2 and Trx-1 occurs during osteoclastogenesis. Adenoviral overexpression of TBP-2 in osteoclast precursors inhibits Trx-1 expression, osteoclast formation, and AP-1 binding activity. TBP-2 and Trx-1 are key regulators of osteoclastogenesis.
引用
收藏
页码：2057 / 2064
页数：8
相关论文
共 50 条
  • [1] Cellular redox regulation by thioredoxin binding protein-2
    Oka, S
    Masutani, H
    Ahsan, K
    Yoshida, T
    Nishinaka, Y
    Nakamura, H
    Yodoi, J
    PROCEEDINGS OF THE MEETING OF THE SOCIETY FOR FREE RADICAL RESEARCH, EUROPEAN SECTION: FREE RADICALS AND OXIDATIVE STRESS: CHEMISTRY, BIOCHEMISTRY AND PATHOPHYSIOLOGICAL IMPLICATIONS, 2003, : 9 - 12
  • [2] THIOL REDOX TRANSITIONS BY THIOREDOXIN AND THIOREDOXIN-BINDING PROTEIN-2 IN CELL SIGNALING
    Yoshihara, Eiji
    Chen, Zhe
    Matsuo, Yoshiyuki
    Masutani, Hiroshi
    Yodoi, Junji
    METHODS IN ENZYMOLOGY, VOL 474: THIOL REDOX TRANSITIONS IN CELL SIGNALING, PT B: CELLULAR LOCALIZATION AND SIGNALING, 2010, 474 : 67 - 82
  • [3] The effects of acrolein on the thioredoxin system: Implications for redox-sensitive signaling
    Myers, Charles R.
    Myers, Judith M.
    Kufahl, Timothy D.
    Forbes, Rachel
    Szadkowski, Adam
    MOLECULAR NUTRITION & FOOD RESEARCH, 2011, 55 (09) : 1361 - 1374
  • [4] The roles of thioredoxin and thioredoxin-binding protein-2 in endometriosis
    Seo, Seok Kyo
    Yang, Hyo In
    Lee, Kyung Eun
    Kim, Hye Yeon
    Cho, SiHyun
    Choi, Young Sik
    Lee, Byung Seok
    HUMAN REPRODUCTION, 2010, 25 (05) : 1251 - 1258
  • [5] Exercise and Glycemic Control: Focus on Redox Homeostasis and Redox-Sensitive Protein Signaling
    Parker, Lewan
    Shaw, Christopher S.
    Stepto, Nigel K.
    Levinger, Itamar
    FRONTIERS IN ENDOCRINOLOGY, 2017, 8
  • [6] Protein S-glutathiolation: Redox-sensitive regulation of protein function
    Hill, Bradford G.
    Bhatnagar, Aruni
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2012, 52 (03) : 559 - 567
  • [7] Identification of redox-sensitive protein interactions in the human cornea
    Lukassen, Marie Vestergaard
    Poulsen, Ebbe Toftgaard
    Enghild, Jan J.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2018, 59 (09)
  • [8] Regulation of redox-sensitive exofacial protein thiols in CHO cells
    Laragione, Teresa
    Gianazza, Elisabetta
    Tonelli, Rossella
    Bigini, Paolo
    Mennini, Tiziana
    Casoni, Filippo
    Massignan, Tania
    Bonetto, Valentina
    Ghezzi, Pietro
    BIOLOGICAL CHEMISTRY, 2006, 387 (10-11) : 1371 - 1376
  • [9] Thioredoxin and thioredoxin-binding protein-2 in cancer and metabolic syndrome
    Kaimul, Ahsan M.
    Nakamura, Hajime
    Masutani, Hiroshi
    Yodoi, Junji
    FREE RADICAL BIOLOGY AND MEDICINE, 2007, 43 (06) : 861 - 868
  • [10] Regulation of UMSBP activities through redox-sensitive protein domains
    Sela, Dotan
    Shlomai, Joseph
    NUCLEIC ACIDS RESEARCH, 2009, 37 (01) : 279 - 288
12345