The porcine respiratory disease complex (PRDC) - a clinical review

被引:9
|
作者
Eddicks, Matthias [1 ]
Eddicks, Lina [2 ]
Stadler, Julia [1 ]
Hermanns, Walter [2 ]
Ritzmann, Mathias [1 ]
机构
[1] Ludwig Maximilians Univ Munchen, Zentrum Klin Tiermed, Klin Schweine, Sonnenstr 16, D-85764 Oberschleissheim, Germany
[2] Ludwig Maximilians Univ Munchen, Zentrum Klin Tiermed, Inst Tierpathol, Munich, Germany
来源
关键词
Pigs; respiratory diseases; therapy resistance; multifactorial disease; vaccination; herd health management; SWINE INFLUENZA-VIRUS; MULTISYSTEMIC WASTING SYNDROME; CIRCOVIRUS TYPE-2 PCV2; IN-SITU HYBRIDIZATION; MYCOPLASMA-HYOPNEUMONIAE VACCINE; LUNG LESIONS; PATHOGEN TRANSMISSION; DUAL INFECTIONS; SLAUGHTER PIGS; ORAL FLUID;
D O I
10.1055/a-1403-1976
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Zusammenfassung Der Porcine Respiratory Disease Complex (PRDC) beschreibt eine klinische Kondition, die sich in Form einer haufig therapieresistenten Atemwegsinfektion bei Mastschweinen manifestiert. Die multifaktorielle Atiologie beinhaltet infektiose und nicht infektiose Faktoren. Bei Entstehung und Verlauf des PRDC spielen neben Management und Hygiene v.a. virale und bakterielle Erreger eine bedeutende Rolle. Das Virus des Porzinen Reproduktiven und Respiratorischen Syndroms (PRRSV), das porzine Circovirus Typ2 (PCV2), Influenza-A-Virus (IAV) und Mycoplasma ( M.) hyopneumoniae stellen die relevantesten Erreger dar. Das klinische Bild und die zugrundeliegenden pathomorphologischen Veranderungen konnen je nach Erregerbeteiligung variieren. Die Komplexitat des PRDC erschwert die Diagnose und auch die Pravention auf Bestandsebene. Der ubersichtsartikel gibt einen Einblick in die Pathomorphologie, Pathogenese sowie Inter-Erreger-Interaktionen und zielt darauf ab, praktizierende Tierarztinnen und Tierarzte bei der Diagnose, Befundinterpretation und Pravention des PRDC zu unterstutzen. Abstract The porcine respiratory disease complex describes a clinical condition that often manifests as treatment-resistant respiratory disease of growing to finishing pigs. Its multifactorial etiology includes infectious and non-infectious factors. Besides management and hygiene conditions, particularly viral and bacterial pathogens contribute to the development and course of PRDC. The porcine reproductive and respiratory syndrome virus (PRRSV), porcine circovirus type 2 (PCV2), influenza A virus (IAV) and Mycoplasma ( M. ) hyopneunoniae are considered as the major pathogens involved in PRDC. The clinical outcome and necropsy findings may differ depending on the involvement of the different pathogens. The complex nature of the PRDC impedes the diagnostic and preventive measures on affected farms. The present review provides insight into the pathomorphology, pathogenesis and inter-pathogen-interactions and aims to support practitioners in implementing purposeful diagnostic and preventive measures.
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页码:120 / 132
页数:13
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