Structure-based design, synthesis, and biological activity study of Hsp90 inhibitors

被引:0
|
作者
Hao, Wenli [1 ]
Ma, Yudao [2 ]
Zhang, Feng [1 ]
Liu, Minyu [3 ]
Song, Chun [1 ]
机构
[1] Shandong Univ, Dept Sch Pharm, Jinan 250012, Shandong, Peoples R China
[2] Shandong Univ, Dept Sch Chem, Jinan 250100, Shandong, Peoples R China
[3] Shanghai Inst Pharmaceut Ind, Dept Sch Pharm, Shanghai 200040, Peoples R China
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
299-MEDI
引用
收藏
页数:1
相关论文
共 50 条
  • [1] Structure-Based Design, Synthesis, and Biological Evaluation of Hsp90β-Selective Inhibitors
    Chaudhury, Subhabrata
    Meka, Penchala Narasimharao
    Banerjee, Monimoy
    Kent, Caitlin N.
    Blagg, Brian S. J.
    CHEMISTRY-A EUROPEAN JOURNAL, 2021, 27 (59) : 14747 - 14764
  • [2] Structure-Based and in silico Design of Hsp90 Inhibitors
    Sgobba, Miriam
    Rastelli, Giulio
    CHEMMEDCHEM, 2009, 4 (09) : 1399 - 1409
  • [3] Design, synthesis, and biological activity of bicyclic radester analogues as Hsp90 inhibitors
    Jadhav, Vinod D.
    Duerfeldt, Adam S.
    Blagg, Brian S. J.
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 19 (24) : 6845 - 6850
  • [4] Structure-based discovery of a new class of Hsp90 inhibitors
    Barril, X
    Brough, P
    Drysdale, M
    Hubbard, RE
    Massey, A
    Surgenor, A
    Wright, L
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2005, 15 (23) : 5187 - 5191
  • [5] Identification of new Hsp90 inhibitors by structure-based virtual screening
    Hong, Tae-Joon
    Park, Hwangseo
    Kim, Yun-Jung
    Jeong, Jae-Hoon
    Hahn, Ji-Sook
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 19 (16) : 4839 - 4842
  • [6] The design, synthesis and biological evaluation of conformationally constrained Hsp90 inhibitors
    Duerfeldt, Adam
    Blagg, Brian
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 237
  • [7] Structure-based drug design targeting Plasmodium falciparum hsp90
    Pillai, Dylan R.
    Corbett, Kevin C.
    Anderson, Marc O.
    DeRisi, Joseph L.
    AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2006, 75 (05): : 97 - 97
  • [8] Design, synthesis, and structures - Activity relationships for chimeric inhibitors of Hsp90
    Shen, Gang
    Wang, Mingwen
    Welch, Timothy R.
    Blagg, Brian S. J.
    JOURNAL OF ORGANIC CHEMISTRY, 2006, 71 (20): : 7618 - 7631
  • [9] A novel class of Hsp90 inhibitors isolated by structure-based virtual screening
    Park, Hwangseo
    Kim, Yun-Jung
    Hahn, Ji-Sook
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2007, 17 (22) : 6345 - 6349
  • [10] Design, synthesis, and biological evaluation of truncated deguelin derivatives as Hsp90 inhibitors
    Yao, Hong
    Xu, Feijie
    Wang, Guangyu
    Xie, Shaowen
    Li, Wenlong
    Yao, Hequan
    Ma, Cong
    Zhu, Zheying
    Xu, Jinyi
    Xu, Shengtao
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 167 : 485 - 498