The origin and evolution of human T-cell lymphotropic virus types I and II

被引:21
|
作者
Suzuki, Y
Gojobori, T
机构
[1] Natl Inst Genet, Ctr Informat Biol, Mishima, Shizuoka 411, Japan
[2] Akita Univ, Sch Med, Dept Microbiol, Akita 010, Japan
关键词
human T-cell lymphotropic virus; molecular evolution; evolutionary rate; phylogenetic tree; genetic variation; geographical distribution;
D O I
10.1023/A:1007953826869
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Studies on human T-cell lymphotropic virus types I (HTLV-I) and II (HTLV-II) are briefly reviewed from the viewpoint of molecular evolution, with special reference to the evolutionary rate and evolutionary relationships among these viruses. In particular, it appears that, in contrast to the low level of variability of HTLV-I among different isolates, individual isolates form quasispecies structures. Elucidating the mechanisms connecting these two phenomena will be one of the future problems in the study of the molecular evolution of HTLV-I and HTLV-II.
引用
收藏
页码:69 / 84
页数:16
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