Cognitive Impairment and Psychiatric Morbidity in HIV plus Zambians with New-Onset Seizure

被引：4

作者：

Kalungwana, Lisa ^{[1
]}

Elafros, Melissa A. ^{[2
]}

Siddiqi, Omar K.

Bositis, Christopher M. ^{[3
]}

Sikazwe, Izukanji ^{[4
]}

Koralnik, Igor J. ^{[5
]}

Theodore, William H. ^{[6
]}

Birbeck, Gretchen L. ^{[7
]}

机构：

[1] Univ Zambia, Dept Psychol, Lusaka, Zambia

[2] Int Neurol & Psychiat Epidemiol Program, E Lansing, MI USA

[3] Greater Lawrence Family Hlth Ctr, Lawrence, MA USA

[4] Ctr Infect Dis Res Zambia, Lusaka, Zambia

[5] Beth Israel Deaconess Med Ctr, Boston, MA 02215 USA

[6] NINDS, NIH, Bethesda, MD 20892 USA

[7] Univ Rochester, Dept Neurol, Strong Epilepsy Ctr, Rochester, NY USA

来源：

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 2014年 / 91卷 / 06期

关键词：

SUB-SAHARAN AFRICA; HEALTH-CARE WORKERS; ANTIRETROVIRAL THERAPY; INFECTION; FREQUENCY; DEMENTIA; INDIVIDUALS; DISORDERS; HIV/AIDS; EPILEPSY;

D O I：

10.4269/ajtmh.13-0758

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

A prospective cohort study of new-onset seizure in people with human immunodeficiency virus (HIV) in Zambia is ongoing to determine the incidence of subsequent epilepsy and risk factors for epileptogenesis in this population. At enrollment, we evaluated this cohort for cognitive impairment and psychiatric morbidity. Over 50% of participants had cognitive impairment and significant psychiatric morbidity. Most participants had advanced HIV disease based on CD4+ T-cell count and World Health Organization stage, but we found no association between cognitive impairment or psychiatric morbidity and HIV disease staging.

引用

页码：1254 / 1258

页数：5

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