Preclinical metrics to predict through-focus visual acuity for pseudophakic patients

被引:76
|
作者
Alarcon, Aixa [1 ]
Canovas, Carmen [1 ]
Rosen, Robert [1 ]
Weeber, Henk [1 ]
Tsai, Linda [2 ]
Hileman, Kendra [2 ]
Piers, Patricia [1 ]
机构
[1] AMO Groningen, NL-9728 NX Groningen, Netherlands
[2] AMO Santa Ana, CA, 1700 East St Andrew Pl, Santa Ana, CA 92705 USA
来源
BIOMEDICAL OPTICS EXPRESS | 2016年 / 7卷 / 05期
关键词
MULTIFOCAL INTRAOCULAR LENSES; MODULATION TRANSFER-FUNCTION; IMAGE QUALITY METRICS; DEFOCUS CURVES; LETTER IDENTIFICATION; OPTICAL-QUALITY; BENCH SYSTEM; PERFORMANCE; PUPIL; ABERRATIONS;
D O I
10.1364/BOE.7.001877
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
This study compares the clinical through-focus visual acuity (VA) in patients implanted with different intraocular lens (IOL) to optical bench testing of the same IOLs to evaluate the suitability of optical metrics of predicting clinical VA. Modulation transfer function and phase transfer function for different spatial frequencies and US Air Force pictures were measured using an optical bench for two monofocal IOLs, three multifocal IOLs and an extended range of vision IOL. Four preclinical metrics were calculated and compared to the clinical through-focus VA collected in three different clinical studies (243 patients in total). All metrics were well correlated (R-2 >= 0.89) with clinical data and may be suitable for predicting through-focus VA in pseudophakic eyes. (C) 2016 Optical Society of America
引用
收藏
页码:1877 / 1888
页数:12
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