Human sperm morphology and in vitro fertilization: sperm tail defects are prognostic for fertilization failure

被引：0
|
作者：
Lim, CC [1 ]
Lewis, SEM [1 ]
Kennedy, M [1 ]
Donnelly, ET [1 ]
Thompson, W [1 ]
机构：
[1] Queens Univ Belfast, Dept Obstet & Gynaecol, Inst Clin Sci, Belfast BT12 6BJ, Antrim, North Ireland
来源：
ANDROLOGIA | 1998年 / 30卷 / 01期
关键词：
sperm; morphology; strict criteria; fertilization;
D O I：
暂无
中图分类号：
R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
摘要：
The aim of this study was to determine the relationship between sperm morphology and fertilization rates in vitro. Semen samples were obtained from 50 couples undergoing IVF treatment. Sperm morphology was classified by strict criteria (Tygerberg) according to head, midpiece and tail defects in neat semen and after sperm selection by Percoll gradient centrifugation. Percoll preparation significantly increased the percentage of sperm with normal morphology from 13 to 20%. However, the greatest single regression coefficient was observed with the percentage of sperm with tail defects and correlated negatively with fertilization rates in vitro both before and after Percoll preparation. Therefore, tail morphology may be of value as a prognostic factor in assisted conception both before and after Percoll preparation.
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页码：43 / 47
页数：5
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