Oxidative Stress Mediates the Spermidine-Induced Degeneration of Retinal Pigment Epithelium in Rats

被引:0
|
作者
Ohashi, K. [1 ]
Fujita, Y. [1 ]
Hirai, S. [1 ]
Shinomiya, K. [1 ]
Katsuta, O. [1 ]
Kawazu, K. [1 ]
Endo, K. [1 ]
Kageyama, M. [1 ]
Nakamura, M. [1 ]
Aono, H. [1 ]
机构
[1] Santen Pharmaceut Co Ltd, Ctr Res & Dev, Ikoma, Japan
关键词
retinal pigment epithelium; oxidation/oxidative or free radical damage; degenerations/dystrophies;
D O I
暂无
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
3644
引用
收藏
页数:3
相关论文
共 50 条
  • [1] Spermidine Oxidation-Mediated Degeneration of Retinal Pigment Epithelium in Rats
    Ohashi, Koji
    Kageyama, Masaaki
    Shinomiya, Katsuhiko
    Fujita-Koyama, Yukie
    Hirai, Shin-ichiro
    Katsuta, Osamu
    Nakamura, Masatsugu
    OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2017, 2017
  • [2] Mitochondrial Oxidative Stress in the Retinal Pigment Epithelium Leads to Localized Retinal Degeneration
    Mao, Haoyu
    Seo, Soo Jung
    Biswal, Manas R.
    Li, Hong
    Conners, Mandy
    Nandyala, Arathi
    Jones, Kyle
    Le, Yun-Zheng
    Lewin, Alfred S.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2014, 55 (07) : 4613 - 4627
  • [3] Alteration of retinal pigment epithelium metabolism mediates retinal degeneration
    Calton, Melissa Ann
    Vollrath, Douglas
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2015, 56 (07)
  • [4] Oxidative stress in retinal pigment epithelium
    Glickman, RD
    Gonzales, MA
    Kumar, N
    Vendal, M
    FREE RADICAL BIOLOGY AND MEDICINE, 1998, 25 : S102 - S102
  • [5] The Retinal Pigment Epithelium has increased oxidative stress and is more susceptible to oxidative stress-induced degeneration in Sorsby Fundus Dystrophy
    Wolk, Alyson
    Upadhyay, Mala
    Ali, Mariya
    Suh, Jason
    Batoki, Julia C.
    Singh, Rupesh
    Bonilha, Vera L.
    Anand-Apte, Bela
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2020, 61 (07)
  • [6] Hydrogen peroxide mediates spermidine-induced autophagy to alleviate salt stress in cucumber
    Zhang, Yuemei
    Wang, Yu
    Wen, Wenxu
    Shi, Zhengrong
    Gu, Qinsheng
    Ahammed, Golam Jalal
    Cao, Kai
    Jahan, Mohammad Shah
    Shu, Sheng
    Wang, Jian
    Sun, Jin
    Guo, Shirong
    AUTOPHAGY, 2021, 17 (10) : 2876 - 2890
  • [7] The retinal pigment epithelium in Sorsby Fundus Dystrophy shows increased sensitivity to oxidative stress-induced degeneration
    Wolk, Alyson
    Upadhyay, Mala
    Ali, Mariya
    Suh, Jason
    Stoehr, Heidi
    Bonilha, Vera L.
    Anand-Apte, Bela
    REDOX BIOLOGY, 2020, 37
  • [8] Heterochromatin inhibits cGAS and STING during oxidative stress-induced retinal pigment epithelium and retina degeneration
    Zou, Ming
    Gong, Lili
    Ke, Qin
    Qi, Ruili
    Zhu, Xingfei
    Liu, Wei
    Sun, Qian
    Tang, Xiangcheng
    Luo, Zhongwen
    Gong, Xiaodong
    Liu, Yizhi
    Li, David Wan-Cheng
    FREE RADICAL BIOLOGY AND MEDICINE, 2022, 178 : 147 - 160
  • [9] Erythropoietin Gene Therapy Delays Retinal Degeneration Resulting from Oxidative Stress in the Retinal Pigment Epithelium
    Biswal, Manas R.
    Wang, Zhaoyao
    Paulson, Ryan J.
    Uddin, Rukshana R.
    Tong, Yao
    Zhu, Ping
    Li, Hong
    Lewin, Alfred S.
    ANTIOXIDANTS, 2021, 10 (06)
  • [10] Early biosignature of oxidative stress in the retinal pigment epithelium
    Arnouk, Hilal
    Lee, Hyunju
    Zhang, Ruonan
    Chung, Hyewon
    Hunt, Richard C.
    Jahng, Wan Jin
    JOURNAL OF PROTEOMICS, 2011, 74 (02) : 254 - 261