Efficacy of Amiodarone on the Heart Failure Patients with Arrhythmia

被引:0
|
作者
Lv, Mingyi [1 ]
Long, X. F. [1 ]
机构
[1] Dalian Univ, Affiliated Zhongshan Hosp, Dept Internal Med, Intens Care Unit, Dalian 116001, Liaoning, Peoples R China
关键词
Amiodarone; arrhythmia; hemodynamic parameters; isosorbide mononitrate sustained release tablets; aspirin enteric-coated tablets; digoxin tablets; ELECTRICAL STORM;
D O I
10.36468/pharmaceutical-sciences.spl.424
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
To investigate the efficacy of amiodarone on the heart failure patients with arrhythmia is the objective of the study. Between April 2018 and April 2020, 86 heart failure patients with arrhythmia who were admitted to the hospital for treatment were enrolled into the study and numbered, and according to the sequence of admission, they were randomized into the control group and observation group, with 43 patients in each group. Patients in two groups received the regular medication, while those in the observation group additionally took amiodarone. We measured the hemodynamic parameters of patients in two groups before and after treatment, including the mean arterial pressure, cardiac output, cardiac index, ejection fraction, fractional shortening and maximal flow velocity in early diastolic stage/maximal flow velocity in advanced diastolic stage, evaluated the efficacy and recorded the incidence rate of adverse reactions. Following the treatment, the effectiveness rate of patients in the observation group was significantly higher than that in the control group (chi(2)=3.927, p<0.05), while the difference in the incidence rates of adverse reactions showed no statistical significance (p>0.05). Amiodarone in treatment of heart failure patients with arrhythmia can improve the heart function and efficacy, and thus it is safe and efficient in clinical practice.
引用
收藏
页码:136 / 139
页数:4
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