Overview of the epidemiology, microbiology, and pathogenesis of Leptospira spp. in humans

被引：219
|
作者：
Plank, R
Dean, D
机构：
[1] Univ Calif San Francisco, Sch Med, Div Infect Dis, San Francisco, CA 94143 USA
[2] Childrens Hosp Oakland, Res Inst, Oakland, CA 94609 USA
来源：
MICROBES AND INFECTION | 2000年 / 2卷 / 10期
关键词：
leptospirosis; epidemiology; virulence; pathogenesis; vaccines;
D O I：
10.1016/S1286-4579(00)01280-6
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Leptospirosis is probably the world's most widespread zoonosis. It remains underdiagnosed largely due to the broad spectrum of signs and symptoms attributable to this spirochetal pathogen. Leptospira spp. cause a diversity of diseases from flu-like illness to Well's syndrome with multi-organ failure. Recent epidemics may herald a change in virulence or an alteration in the balance between humans and their interactions with other host species and the environment. (C) 2000 Editions scientifiques et medicales Elsevier SAS.
引用
收藏
页码：1265 / 1276
页数：12
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