Recombinant Porcine Factor VIII, Obi-1, Successfully Controlled Gastrointestinal Bleeding in a Patient with Acquired Hemophilia A

被引:1
|
作者
Riaz, Muhammad Kashif [1 ]
Girnius, Saulius [2 ]
Palascak, Joseph Edward [3 ]
机构
[1] Univ Cincinnati, Med Ctr, Cincinnati, OH 45267 USA
[2] Univ Cincinnati, Med Ctr, Hematol Oncol, Cincinnati, OH 45267 USA
[3] Univ Cincinnati, Med Ctr, Hematol, Cincinnati, OH 45267 USA
关键词
D O I
10.1182/blood.V126.23.4676.4676
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页数:3
相关论文
共 50 条
  • [1] Overview of the structure and manufacturing process for OBI-1, a recombinant porcine sequence, factor VIII for the treatment of acquired hemophilia A
    Wojciechowski, Peter
    Lai, Chee Kong
    Xiong, Yi
    Deer, Frank
    [J]. HAEMOPHILIA, 2014, 20 : 181 - 181
  • [2] The Effect of Inhibitory Antibodies on Acute Treatment of Bleeding Episodes with OBI-1, an Antihemophilic Factor VIII (recombinant), Porcine Sequence, in Patients with Acquired Hemophilia A
    Farin, Heinrich D.
    Novack, Aaron
    Mo, Min
    Bourgeois, Christelle
    Horling, Frank M.
    Ewenstein, Bruce M.
    [J]. BLOOD, 2014, 124 (21)
  • [3] The Benefit of FVIII Measurement: Tailored Treatment with Obi-1, a Recombinant Porcine Sequence Factor VIII, in Subjects with Acquired Hemophilia a
    Oladapo, Abiola
    Epstein, Joshua
    Novack, Aaron
    Farin, Heinrich D.
    [J]. BLOOD, 2014, 124 (21)
  • [4] OBI-1, porcine recombinant Factor VIII for the potential treatment of patients with congenital hemophilia A and alloantibodies against human Factor VIII
    Toschi, Vincenzo
    [J]. CURRENT OPINION IN MOLECULAR THERAPEUTICS, 2010, 12 (05) : 617 - 625
  • [5] Efficacy and safety of B-domain deleted recombinant porcine factor VIII (OBI-1) in the treatment of acquired hemophilia A: interim results
    Greist, A.
    Shapiro, A.
    Kruse-Jarres, R.
    St Louis, J.
    Smith, H.
    Gomperts, E.
    [J]. HAEMOPHILIA, 2012, 18 : 1 - 1
  • [6] Efficacy and safety of OBI-1, an antihaemophilic factor VIII (recombinant), porcine sequence, in subjects with acquired haemophilia A
    Kruse-Jarres, R.
    St-Louis, J.
    Greist, A.
    Shapiro, A.
    Smith, H.
    Chowdary, P.
    Drebes, A.
    Gomperts, E.
    Bourgeois, C.
    Mo, M.
    Novack, A.
    Farin, H.
    Ewenstein, B.
    [J]. HAEMOPHILIA, 2015, 21 (02) : 162 - 170
  • [7] Recombinant B-Domain Deleted Porcine Factor VIII (OBI-1) Safety and Efficacy in the Treatment of Acquired Hemophilia A: Interim Results
    St Louis, Jean
    Kruse-Jarres, Rebecca
    Greist, Anne
    Shapiro, Amy D.
    Smith, Hedy
    Drebes, Anja B.
    Lozier, Jay N.
    Gomperts, Edward D.
    [J]. BLOOD, 2012, 120 (21)
  • [8] Treatment of serious bleeds with an antihaemophilic factor VIII (recombinant), porcine sequence (OBI-1) in patients with acquired haemophilia A
    Kruse-Jarres, R.
    St-Louis, J.
    Greist, A.
    Shapiro, A.
    Smith, H.
    Chowdary, P.
    Drebes, A.
    Gomperts, E.
    Bourgeois, C.
    Mo, M.
    Novack, A.
    Farin, H.
    Ewenstein, B.
    [J]. HAEMOPHILIA, 2015, 21 : 62 - 62
  • [9] Recombinant porcine sequence factor VIII (OBI-1): Results from a prospective clinical study investigating the treatment of serious bleeds in patients with acquired hemophilia A
    Kruse-Jarres, R.
    St-Louis, J.
    Greist, A.
    Shapiro, A.
    Smith, H.
    Chowdary, P.
    Drebes, A.
    Gomperts, E.
    Chapman, M.
    Mo, M.
    Novack, A.
    Farin, H.
    [J]. HAEMOPHILIA, 2014, 20 : 1 - 1
  • [10] TREATMENT OF SERIOUS BLEEDS IN A PROSPECTIVE CLINICAL TRIAL WITH A B-DOMAIN DELETED RECOMBINANT PORCINE SEQUENCE FACTOR VIII (OBI-1) IN PATIENTS WITH ACQUIRED HEMOPHILIA A
    Kruse-Jarres, Rebecca
    St-Louis, Jean
    Greist, Anne
    Shapiro, Amy
    Smith, Hedy
    Chowdary, Pratima
    Drebes, Anja
    Gomperts, Edward
    Chapman, Miranda
    Mo, Min
    Novack, Aaron
    Farin, Heinrich
    [J]. AMERICAN JOURNAL OF HEMATOLOGY, 2014, 89 (06) : E41 - E42