Seven Novel Linear Polyketides from Xylaria sp NCY2

被引：32
|
作者：
Hu, Zhi-Yu [1 ]
Li, Yao-Yao [1 ]
Lu, Chun-Hua [1 ]
Lin, Ting [1 ]
Hu, Ping [1 ]
Shen, Yue-Mao [1 ]
机构：
[1] Xiamen Univ, Sch Life Sci, Fujian Engn Lab Pharmaceut,Key Lab Minist Educ Ce, Xiamen Engn Res Ctr Marine Microbial Drug Discove, Xiamen 361005, Peoples R China
来源：
HELVETICA CHIMICA ACTA | 2010年 / 93卷 / 05期
关键词：
SOUTH CHINA SEA; FUNGUS; SESQUITERPENOIDS; BIOSYNTHESIS; XANTHONES; SORDARIN; RECEPTOR; ACID;
D O I：
10.1002/hlca.200900323
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Seven novel polyketides, namely, 1-(xylarenone A)xylariate A (1), xylarioic acid B (2), xylariolide A (3), xylariolide B (4), xylariolide C (5), methyl xylariate C (6), and xylariolide D(7), together with the known one taiwapyrone (8), were isolated from the endophytic fungal strain xylaria sp. NCY2 of Torreya jackii CHUN. Their structures were elcidated by spectroscopic analyses, including 1D- and 2D-NMR experiments, and on the basis of HR-Q-TOF mass spectometry. Antitumor and antibacterial assays of compounds 1-8 were carried out, which show moderate activities.
引用
收藏
页码：925 / 933
页数：9
相关论文
共 50 条
  • [1] Three new sesquiterpenoids from Xylaria sp NCY2
    Hu, Zhi-Yu
    Li, Yao-Yao
    Huang, Yao-Jian
    Su, Wen-Jin
    Shen, Yue-Mao
    [J]. HELVETICA CHIMICA ACTA, 2008, 91 (01) : 46 - 52
  • [2] Novel polyketides isolated from Streptomyces sp.
    Li, Jian
    Lu, Chun-Hua
    Shen, Yue-Mao
    [J]. HELVETICA CHIMICA ACTA, 2008, 91 (04) : 741 - 745
  • [3] Isokibdelones:: Novel heterocyclic polyketides from a Kibdelosporangium sp.
    Ratnayake, Ranjala
    Lacey, Ernest
    Tennant, Shaun
    Gill, Jennifer H.
    Capon, Robert J.
    [J]. ORGANIC LETTERS, 2006, 8 (23) : 5267 - 5270
  • [4] Xyloketal G, a novel metabolite from the mangrove fungus Xylaria sp. 2508
    Wu, XY
    Liu, XH
    Jiang, GC
    Lin, YC
    Chan, W
    Vrijmoed, LLP
    [J]. CHEMISTRY OF NATURAL COMPOUNDS, 2005, 41 (01) : 27 - 29
  • [5] Xyloketal G, a Novel Metabolite from the Mangrove Fungus Xylaria sp. 2508
    Xiongyu Wu
    Xiaohong Liu
    Guangce Jiang
    Yongcheng Lin
    Willy Chan
    L. L. P. Vrijmoed
    [J]. Chemistry of Natural Compounds, 2005, 41 : 27 - 29
  • [6] Acremoxanthones A and B, novel antibiotic polyketides from the fungus Acremonium sp BCC 31806
    Isaka, Masahiko
    Palasarn, Somporn
    Auncharoen, Patchanee
    Kornmijit, Somjit
    Jones, E. B. Gareth
    [J]. TETRAHEDRON LETTERS, 2009, 50 (03) : 284 - 287
  • [7] Biselides A-E: novel polyketides from the Okinawan ascidian Didemnidae sp.
    Teruya, T
    Suenaga, K
    Maruyama, S
    Kurotaki, M
    Kigoshi, H
    [J]. TETRAHEDRON, 2005, 61 (27) : 6561 - 6567
  • [8] A novel pestalotin 4-methyl-β-mannopyranoside from the endophytic fungus Xylaria sp.
    Rivera-Chavez, J.
    Figueroa, M.
    del Carmen Gonzalez, M.
    Mata, R.
    [J]. PLANTA MEDICA, 2014, 80 (10) : 772 - 773
  • [9] A Novel Steroid Derivative and A New Steroidal Saponin from Endophytic Fungus Xylaria sp.
    Li, Wei
    Yang, Xue-Qiong
    Yang, Ya-Bin
    Zhao, Li-Xing
    Zhou, Qing-Yan
    Zhang, Zhuo-Xi
    Zhou, Hao
    Hu, Ming
    Ruan, Bao-Hui
    Ding, Zhong-Tao
    [J]. NATURAL PRODUCT COMMUNICATIONS, 2017, 12 (06) : 901 - 904
  • [10] (+)- and (-)-Ascomlactone A: a pair of novel dimeric polyketides from a mangrove endophytic fungus Ascomycota sp SK2YWS-L
    Liu, Zhaoming
    Chen, Senhua
    Qiu, Pei
    Tan, Chunbing
    Long, Yuhua
    Lu, Yongjun
    She, Zhigang
    [J]. ORGANIC & BIOMOLECULAR CHEMISTRY, 2017, 15 (48) : 10276 - 10280
12345