Reactive oxygen species (ROS) dependent antibacterial effects of graphene oxide coatings

被引:0
|
作者
Zhao, C. [1 ,4 ]
Zhang, L. [2 ]
Wu, H. [3 ]
Song, X. [4 ]
Chen, Y. [3 ]
Liu, D. [4 ]
Lei, P. [4 ]
Li, L. [4 ]
Cui, B. [1 ]
机构
[1] Hubei Polytech Univ, Sch Med, Huangshi 435003, Hubei, Peoples R China
[2] Naval Med Univ, Changhai Hosp, Dept Pharm, Shanghai 200433, Peoples R China
[3] Xinxiang Med Univ, Sch Publ Hlth, Xinxiang 453003, Henan, Peoples R China
[4] Xinxiang Med Univ, Sch Life Sci & Technol, Xinxiang 453003, Henan, Peoples R China
关键词
Reactive oxygen species; Graphene oxide; Antibacterial activity;
D O I
暂无
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
The antibacterial mechanism of GO in solution have been well studied, however, the antibacterial activity of GO as coating material in solid phase is still unclear. Here, we report a direct proof of the antibacterial mechanisms of GO coatings. Oxidative stress induced by GO coating was found to be an important reason for the prevention of bacteria colonization on the coating surface, since a ROS dependent antibacterial effect was detected in this study. This finding could help with understanding bacteria-GO solid surface interaction and further designing such antibacterial implant surfaces.
引用
收藏
页码:481 / 489
页数:9
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