Binding affinities of HMUTSα for 6-thioguanine and methyl-6-thioguanine in DNA duplexes:: A basis for lesion toxicity

被引：0
|
作者：
Koh, CZ
Dunham, SU
Baitinger, C
Modrich, P
机构：
[1] Colby Coll, Dept Chem, Waterville, ME 04901 USA
[2] Duke Univ, Med Ctr, Howard Hughes Med Inst, Durham, NC 27706 USA
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2004年 / 227卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
138-CHED
引用
收藏
页码：U423 / U423
页数：1
相关论文
共 50 条
  • [1] Structural analysis of 6-thioguanine and methyl-6-thioguanine in DNA duplexes
    Dunham, SU
    Rodwell, M
    Olson, HE
    FASEB JOURNAL, 2003, 17 (04): : A180 - A180
  • [2] Effect of 6-thioguanine and methyl-6-thioguanine on stability of DNA duplexes.
    Dunham, SU
    Mabaera, R
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2002, 223 : U208 - U208
  • [3] Quantification of 6-thioguanine and S6-methylthioguanine in genomic DNA of human cells treated with 6-thioguanine and the identification of cellular proteins binding to thioguanine-bearing duplex DNA
    Wang, Hongxia
    Wang, Yinsheng
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2010, 239
  • [4] Effect of 6-thioguanine on the stability of duplex DNA
    Bohon, J
    de los Santos, CR
    NUCLEIC ACIDS RESEARCH, 2005, 33 (09) : 2880 - 2886
  • [5] Cytotoxic mechanism of 6-thioguanine: hMutS alpha, the human mismatch binding heterodimer, binds to DNA containing S-6-methylthioguanine
    Waters, TR
    Swann, PF
    BIOCHEMISTRY, 1997, 36 (09) : 2501 - 2506
  • [6] MUTYH mediates the toxicity of combined DNA 6-thioguanine and UVA radiation
    Grasso, Francesca
    Ruggieri, Vitalba
    De Luca, Gabriele
    Leopardi, Paola
    Mancuso, Maria Teresa
    Casorelli, Ida
    Pichierri, Pietro
    Karran, Peter
    Bignami, Margherita
    ONCOTARGET, 2015, 6 (10) : 7481 - 7492
  • [7] THE EFFECTS OF INHIBITORS OF DNA BIOSYNTHESIS ON THE CYTO-TOXICITY OF 6-THIOGUANINE
    LEE, SH
    SARTORELLI, AC
    CANCER BIOCHEMISTRY BIOPHYSICS, 1981, 5 (03): : 189 - 194
  • [8] Mutagenic consequences of the incorporation of 6-thioguanine into DNA
    UribeLuna, S
    QuintanaHau, JD
    MaldonadoRodriguez, R
    EspinosaLara, M
    Beattie, KL
    Farquhar, D
    Nelson, JA
    BIOCHEMICAL PHARMACOLOGY, 1997, 54 (03) : 419 - 424
  • [9] Stability of DNA duplexes containing 6-thioguanine.
    Dunham, SU
    Mabaera, R
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2001, 221 : U197 - U197
  • [10] UNILATERAL CHROMATID DAMAGE - A NEW BASIS FOR 6-THIOGUANINE CYTO-TOXICITY
    MAYBAUM, J
    MANDEL, HG
    CANCER RESEARCH, 1983, 43 (08) : 3852 - 3856
12345