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- [10] Cytoskeleton of MollicutesJOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY, 2006, 11 (3-5) : 256 - 264Miyata, MakotoOgaki, Hiroshi
Loss and gain of GroEL in the Mollicutes
被引：0
|作者：
Clark, Gregory W.
[1
,2
]
Tillier, Elisabeth R. M.
[1
,2
]
机构：
[1] Univ Hlth Network, Ontario Canc Inst, Toronto, ON M5G 1L7, Canada
[2] Univ Toronto, Dept Med Biophys, Toronto, ON M5G 1L7, Canada
来源：
基金：
加拿大健康研究院;
关键词：
Mycoplasma;
GroEL;
invasin;
lateral gene transfer;
GASTRIC EPITHELIAL-CELLS;
HEAT-SHOCK PROTEINS;
MYCOPLASMA-PNEUMONIAE;
ESCHERICHIA-COLI;
HELICOBACTER-PYLORI;
INTRACELLULAR LOCATION;
HYDROGEN-PEROXIDE;
BACILLUS-SUBTILIS;
ELECTRON-MICROSCOPY;
BACTERIAL-GROWTH;
D O I：
10.1139/O09-157
中图分类号：
Q5 [生物化学];
Q7 [分子生物学];
学科分类号：
071010 ;
081704 ;
摘要：
GroEL is a chaperone thought of as essential for bacterial life. However, some species of Mollicutes are missing GroEL. We use phylogenetic analysis to show that the presence of GroEL is polyphyletic among the Mollicutes, and that there is evidence for lateral gene transfer of GroEL to Mycoplasma penetrans from the Proteobacteria. Furthermore, we propose that the presence of GroEL in Mycoplasma may be required for invasion of host tissue, suggesting that GroEL may act as an adhesin-invasin.
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页码：185 / 194
页数：10
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