Role of the TPR-domain of AIPL1 in its function as PDE6 chaperone

被引：0
|
作者：
Artemyev, Nikolai [1 ]
Yu, Liping [2 ,3 ]
Yadav, Ravi [1 ]
机构：
[1] Univ Iowa, Mol Physiol & Biophys, Iowa City, IA USA
[2] Univ Iowa, Biochem, Iowa City, IA USA
[3] Univ Iowa, CCOM NMR Facil, Iowa City, IA USA
来源：
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE | 2019年 / 60卷 / 09期
关键词：
D O I：
暂无
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
4932
引用
收藏
页数：2
相关论文
共 32 条
  • [1] The chaperone function of the LCA protein AIPL1 - AIPL1 chaperone function
    van der Spuy, J
    Cheetham, ME
    RETINAL DEGENERATIVE DISEASES, 2006, 572 : 471 - 476
  • [2] The integrity and organization of the human AIPL1 functional domains is critical for its role as a HSP90-dependent co-chaperone for rod PDE6
    Sacristan-Reviriego, Almudena
    Bellingham, James
    Prodromou, Chrisostomos
    Kumaran, Neruban
    Bainbridge, James
    Michaelides, Michel
    van der Spuy, Jacqueline
    HUMAN MOLECULAR GENETICS, 2017, 26 (22) : 4465 - 4480
  • [3] Unique Proline-Rich Domain Regulates the Chaperone Function of AIPL1
    Li, Jing
    Zoldak, Gabriel
    Kriehuber, Thomas
    Soroka, Joanna
    Schmid, Franz X.
    Richter, Klaus
    Buchner, Johannes
    BIOCHEMISTRY, 2013, 52 (12) : 2089 - 2096
  • [4] Heterologous Expression of Functional PDE6 Requires Cooperative Action of AIPL1 and the Inhibitory Pγ-subunit
    Gopalakrishna, Kota
    Boyd, Kimberly
    Artemyev, Nikolai
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2016, 57 (12)
  • [5] AIPL1, a Protein Associated with Childhood Blindness, Interacts with α-Subunit of Rod Phosphodiesterase (PDE6) and Is Essential for Its Proper Assembly
    Kolandaivelu, Saravanan
    Huang, Jing
    Hurley, James B.
    Ramamurthy, Visvanathan
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 284 (45) : 30853 - 30861
  • [6] The integrity and organization of the human AIPL1 functional domains is critical for its role as a HSP90-dependent co-chaperone for rod PDE6 (vol 26, pg 4465, 2017)
    Sacristan-Reviriego, Almudena
    Bellingham, James
    Prodromou, Chrisostomos
    Boehm, Annika N.
    Aichem, Annette
    Kumaran, Neruban
    Bainbridge, James
    Michaelides, Michel
    van der Spuy, Jacqueline
    HUMAN MOLECULAR GENETICS, 2018, 27 (07) : 1309 - 1309
  • [7] Chaperone ligand-discrimination by the TPR-domain protein Tah1
    Millson, Stefan H.
    Vaughan, Cara K.
    Zhai, Chao
    Ali, Maruf M. U.
    Panaretou, Barry
    Piper, Peter W.
    Pearl, Laurence H.
    Prodromou, Chrisostomos
    BIOCHEMICAL JOURNAL, 2008, 413 (261-268) : 261 - 268
  • [8] AIPL1 Protein and its Indispensable Role in Cone Photoreceptor Function and Survival
    Kolandaivelu, Saravanan
    Ramamurthy, Visvanathan
    RETINAL DEGENERATIVE DISEASES: MECHANISMS AND EXPERIMENTAL THERAPY, 2014, 801 : 43 - 48
  • [9] Structural Study of AIPL1: Molecular Basis of its Function and its Role in Blinding Diseases
    Gupta, Chitrak
    Hayes, Abigail
    Distefano, Mark D.
    Ramamurthy, Visvanathan
    Mertz, Blake
    BIOPHYSICAL JOURNAL, 2015, 108 (02) : 222A - 222A
  • [10] Molecular Mechanisms of AIPL1 and its TPR domain in Leber congenital amaurosis 4 (LCA4) a severe form of childhood blindness
    Yadav, Ravi Prakash
    Ghakar, Lokesh
    Yu, Liping
    Artemyev, Nikolai O.
    ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2018, 74 : A464 - A464
1234