Azalide 3,6-ketals: Antibacterial activity and structure-activity relationships of aryl and hetero aryl substituted analogues

被引：3

作者：

Sakya, SM ^{[1
]}

Bertinato, P ^{[1
]}

Pratt, B ^{[1
]}

Suarez-Contreras, M ^{[1
]}

Lundy, KM ^{[1
]}

Minich, ML ^{[1
]}

Cheng, HM ^{[1
]}

Ziegler, CB ^{[1
]}

Kamicker, BJ ^{[1
]}

Hayashi, SF ^{[1
]}

Santoro, SL ^{[1
]}

George, DM ^{[1
]}

Bertsche, CD ^{[1
]}

机构：

[1] Pfizer Inc, Vet Med Res & Dev, Groton, CT 06340 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2003年 / 13卷 / 07期

关键词：

D O I：

10.1016/S0960-894X(03)00100-8

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Aryl and hetero aryl substituted 3,6-ketals of 15-membered azalide analogues were synthesized and were found to have potent in vitro antibacterial activity against veterinary pathogens, including Staphylococcus aureus and Pasteurella multocida. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：1373 / 1375

页数：3

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