End-stage heart failure: Two surgical approaches with different rehabilitative outcomes

被引:5
|
作者
Racca, Vittorio [1 ]
Castiglioni, Paolo [2 ]
Panzarino, Claudia [1 ]
Oliva, Fabrizio [3 ]
Perna, Enrico [3 ]
Ferratini, Maurizio [1 ]
机构
[1] Fdn Don C Gnocchi, Santa Maria Nascente Inst IRCCS, Cardiol Rehabil Ctr, Milan, Italy
[2] Fdn Don C Gnocchi, Santa Maria Nascente Inst IRCCS, Biomed Technol Dept, Milan, Italy
[3] Osped Niguarda Ca Granda, De Gasperis Cardio Ctr, Milan, Italy
来源
PLOS ONE | 2017年 / 12卷 / 10期
关键词
VENTRICULAR ASSIST DEVICE; INTERNATIONAL SOCIETY; TRANSPLANTATION; INDEX;
D O I
10.1371/journal.pone.0185717
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Background A rising number of patients are surgically treated for heart failure at the more advanced stage, thanks to the increasing use of left ventricular assist device (LVAD) as a reliable alternative to heart transplantation (HTx). However, it is still unknown whether differences exist between the two surgical approaches in the efficacy of rehabilitation programmes. Therefore, aim of this study was to evaluate whether functional capacity and rehabilitative outcomes differ between HTx and implantation of LVAD. Methods and results We enrolled 51 patients with HTx and 46 with LVAD upon admission to our rehabilitationunit. We evaluated six-minute walking test (6MWT), resting oxygen saturation (SaO(2)) and nutritional assessment before and after a standardised cardiovascular rehabilitation programme. HTx and LVAD groups differed in age, anthropometric variables, gender distribution. Upon enrolment, 6MWT distance was similar in the two groups, whereas malnutrition was less frequent and the waist circumference/height ratio (WHtR) was greater in LVAD patients. SaO(2) was greater in HTx patients. Rehabilitation improved SaO(2), 6MWT distance and nutritional status. The difference in malnutrition disappeared, but WHtR remained higher in the LVAD and SaO(2) higher in the HTx patients; the 6MWT distance improved more in the HTx patients. Multivariate linear regression analysis confirmed that the type of intervention was independent predictor of 6MWT distance after rehabilitation. Conclusions HTx patients improve more rapidly and perform better after rehabilitation, suggesting the need for more tailored rehabilitation training for LVAD patients.
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页数:12
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