Calcium signalling: Ringing changes to the 'bell-shaped curve'

被引:30
|
作者
Bootman, MD [1 ]
Lipp, P [1 ]
机构
[1] Babraham Inst, Mol Signalling Lab, Cambridge CB2 4AT, England
关键词
D O I
10.1016/S0960-9822(00)80072-X
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The 'bell-shaped' curve relating cytosolic Ca2+ concentration to IP3 receptor activation is considered important in the generation of the complex Ca2+ signals seen inside many cells. But recent findings suggest this bimodal relationship is not always evident and may not apply to some IP3 receptor isoforms.
引用
收藏
页码:R876 / R878
页数:3
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