Paediatric manifestations of Langerhans cell histiocytosis: A review of the clinical and radiological findings

Langerhans cell histiocytosis is a rare disease in children. However, its ability to present in many ways, to mimic other conditions, and to manifest itself in many organs makes it a fascinating disease for radiologists. This article reviews the history of the disease, the features that are most useful in determining prognosis, and the various radiological findings seen in paediatric patients. (C) 2003 The Royal College of Radiologists. Published by Elsevier Science Ltd. All rights reserved.