Efficacy and Safety of Macitentan in Patients with Portopulmonary Hypertension: The Randomized, Placebo Controlled Portico Trial

被引:0
|
作者
Krowka, Michael J. [1 ]
Cottreel, Emmanuelle [2 ]
De Groote, Pascal [3 ]
Hoeper, Marius M. [4 ,5 ]
Kim, Nick [6 ]
Martin, Nicolas [2 ]
Savale, Laurent [7 ]
Sitbon, Olivier [7 ]
Bosch, Jaime [8 ,9 ]
机构
[1] Mayo Clin Rochester, Rochester, MN USA
[2] Actel Pharmaceut Ltd, Allschwil, Switzerland
[3] CHRU Lille, Inst Pasteur Lille, Serv Cardiol, Inst Coeur Poumon,Inserm,U1167, Lille, France
[4] Hannover Med Sch, Hannover, Germany
[5] German Ctr Lung Res, Hannover, Germany
[6] Univ Calif San Diego, San Diego, CA 92103 USA
[7] Univ Paris Saclay, Univ Paris Sud, Hop Bicetre, Aphp,Inserm,Umr S999, Le Kremlin Bicetre, France
[8] Univ Barcelona, Hosp Clin Idibaps, Barcelona, Spain
[9] Univ Barcelona, Ciberehd, Barcelona, Spain
关键词
D O I
暂无
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
111
引用
收藏
页码:70A / 71A
页数:2
相关论文
共 50 条
  • [1] Late Breaking Abstract - Efficacy and safety of macitentan in portopulmonary hypertension: the PORTICO trial
    Sitbon, Olivier
    Bosch, Jaume
    Cottreel, Emmanuelle
    De Groote, Pascal
    Hoeper, Marius M.
    Krowka, Michael
    Martin, Nicolas
    Savale, Laurent
    Kim, Nick
    EUROPEAN RESPIRATORY JOURNAL, 2018, 52
  • [2] Macitentan for the treatment of portopulmonary hypertension (PORTICO): a multicentre, randomised, double-blind, placebo-controlled, phase 4 trial
    Sitbon, Olivier
    Bosch, Jaume
    Cottreel, Emmanuelle
    Csonka, Denes
    de Groote, Pascal
    Hoeper, Marius M.
    Kim, Nick H.
    Martin, Nicolas
    Savale, Laurent
    Krowka, Michael
    LANCET RESPIRATORY MEDICINE, 2019, 7 (07): : 594 - 604
  • [3] PORTICO: First Randomized Controlled Trial of Vasomodulator Therapy in Portopulmonary Hypertension
    Raevens, Sarah
    Fallon, Michael B.
    HEPATOLOGY, 2020, 71 (05) : 1870 - 1872
  • [4] PHARMACOKINETICS OF MACITENTAN IN PATIENTS WITH PORTOPULMONARY HYPERTENSION: FINDINGS FROM THE PORTICO SUB-STUDY
    Church, C. A.
    Bosch, J.
    Cottreel, E.
    Csonka, D.
    Hoeper, M.
    Krowka, M.
    Martin, N.
    Kim, N. H.
    Sitbon, O.
    THORAX, 2018, 73 : A105 - A105
  • [5] Macitentan Improves Risk Categorization for Liver Transplant Mortality in Patients With Portopulmonary Hypertension: A PORTICO Study Post Hoc Analysis
    Krowka, Michael
    Cottreel, Emmanuelle
    Hoeper, Marius M.
    Kim, Nick H.
    Martin, Nicolas
    Sitbon, Olivier
    Bosch, Jaume
    LIVER TRANSPLANTATION, 2020, 26 (07) : 935 - 940
  • [6] Placebo Effect and Efficacy of Nebivolol in Patients with Hypertension not Controlled with Lisinopril or Losartan: A Phase IV, Randomized, Placebo-Controlled Trial
    Robert J. Weiss
    Manfred Stapff
    Yuhua Lin
    American Journal of Cardiovascular Drugs, 2013, 13 : 129 - 140
  • [7] Placebo Effect and Efficacy of Nebivolol in Patients with Hypertension not Controlled with Lisinopril or Losartan: A Phase IV, Randomized, Placebo-Controlled Trial
    Weiss, Robert J.
    Stapff, Manfred
    Lin, Yuhua
    AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS, 2013, 13 (02) : 129 - 140
  • [8] Efficacy and safety of tadalafil in portopulmonary hypertension
    Jevnikar, Mitja
    Ebstein, Nathan
    Jais, Xavier
    Boucly, Athenais
    Montani, David
    Humbert, Marc
    Sitbon, Olivier
    Savale, Laurent
    EUROPEAN RESPIRATORY JOURNAL, 2018, 52
  • [9] Efficacy and Safety of Upacicalcet in Hemodialysis Patients with Secondary Hyperparathyroidism A Randomized Placebo-Controlled Trial
    Shigematsu, Takashi
    Koiwa, Fumihiko
    Isaka, Yoshitaka
    Fukagawa, Masafumi
    Hagita, Keiko
    Watanabe, Yukihisa S.
    Honda, Daisuke
    Akizawa, Tadao
    CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2023, 18 (10): : 1300 - 1309
  • [10] Randomized placebo-controlled trial comparing efficacy and safety of valdecoxib with naproxen in patients with osteoarthritis
    Kivitz, A
    Eisen, G
    Zhao, WW
    Bevirt, T
    Recker, DP
    JOURNAL OF FAMILY PRACTICE, 2002, 51 (06): : 530 - 537