Effects of bariatric surgery on bone

被引:8
|
作者
Uebelhart, Brigitte [1 ]
机构
[1] Hop Cantonal Univ Geneva, Serv Malad Osseuses, Dept Specialites Med, Fac Med Geneve, 4 Rue Gabrielle Perret Gentil, CH-1205 Geneva, Switzerland
关键词
Bone mineral density; Fractures; Biochemical bone turnover markers; Y GASTRIC BYPASS; MINERAL METABOLISM; PARATHYROID-HORMONE; LONG-TERM; OBESITY; DENSITY; DEFICIENCY; TURNOVER; INCREASE; CALCIUM;
D O I
10.1016/j.jbspin.2016.02.013
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Bariatric surgery currently relies on combinations of restrictive and malabsorptive procedures. Early decreases in bone mineral density (BMD) have been reported. However, the accuracy of dual-energy X-ray absorptiometry used to measure BMD can be diminished by the major weight loss, whereas quantitative computed tomography (QCT) measurements are less affected. The nutritional deficiencies induced by mixed bariatric surgery procedures, together with changes in hormones produced by adipocytes and/or the gastrointestinal tract, are often associated with elevations in serum levels of bone resorption markers. Although the data are limited, the incidence of fractures does not seem higher after bariatric surgery than in non-operated obese patients. (C) 2016 Societe francaise de rhumatologie. Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:271 / 275
页数:5
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