Spike in Diabetic Ketoacidosis Rates in Pediatric Type 2 Diabetes During the COVID-19 Pandemic

被引:36
|
作者
Chao, Lily C. [1 ,2 ]
Vidmar, Alaina P. [1 ,2 ]
Georgia, Senta [1 ,2 ,3 ]
机构
[1] Childrens Hosp Los Angeles, Diabet & Obes Program, Ctr Endocrinol Diabet & Metab, Los Angeles, CA 90027 USA
[2] Univ Southern Calif, Dept Pediat, Keck Sch Med, Los Angeles, CA 90007 USA
[3] Univ Southern Calif, Dept Stem Cell Biol & Regenerat Med, Keck Sch Med, Los Angeles, CA 90007 USA
基金
美国国家卫生研究院;
关键词
D O I
10.2337/dc20-2733
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVE The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) on the incidence of new-onset type 2 diabetes and diabetic ketoacidosis (DKA) is unclear. It is unknown whether the coincidence of DKA noted in adult patients with type 2 diabetes is an issue for youth during the coronavirus disease 2019 pandemic. RESEARCH DESIGN AND METHODS A retrospective single-center medical record review was conducted in a large, urban children's hospital of pediatric subjects presenting with new-onset type 2 diabetes between March and August of 2018 to 2020. RESULTS The proportion of subjects presenting with new-onset type 2 diabetes in DKA dramatically increased in 2020 (9% in 2018, 3% in 2019, and 20% in 2020, P = 0.029). CONCLUSIONS In 2020, youth with new-onset type 2 diabetes had a greater incidence of DKA at presentation than previously observed. Future studies should examine the impact of SARS-CoV2 exposure on the presentation of type 2 diabetes in all age-groups to inform better patient care.
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页码:1451 / 1453
页数:3
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