Genetic control of intra-uterine growth

被引:13
|
作者
Devriendt, K [1 ]
机构
[1] Univ Hosp Gasthuisberg, Ctr Human Genet, B-3000 Louvain, Belgium
关键词
imprinting; uniparental disomy; syndrome; intrauterine growth restriction;
D O I
10.1016/S0301-2115(00)00422-X
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
The expression of a few genes in the human genome depends on whether they are located on the maternal or on the paternal chromosome. This phenomenon is called genomic imprinting. Several of these genes have a role in normal embryonic and fetal growth, as indicated by an abnormal development associated with disturbed genomic imprinting. This has lead to the suggestion that the genomic imprinting has evolved as a mechanism to regulate embryonic and fetal growth. (C) 2000 Elsevier Science Ireland Ltd. All rights reserved.
引用
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页码:29 / 34
页数:6
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