Simplified Bernoulli formula to predict flow limiting stenosis at coronary computed tomography angiography

Objective: To compare the diagnostic performance of estimated energy loss (EEL) with diameter stenosis (DS) to estimate significant stenosis by fractional flow reserve (FFR). Materials and methods: One hundred twenty-five patients were included. EEL was calculated using DS, lesion length, minimal lumen area and left ventricular volume. FFR <= 0.80 was determined significant. Results: EEL improved the accuracy from 63% (95% confidence interval (CI): 55-72%) to 83% (95% CI: 75-89%, p < 0.0001). EEL increased the area under the receiver operating characteristics curve from 0.63 to 0.85 (p < 0.0001). Conclusions: EEL improved the diagnostic performance to detect functionally significant stenosis than DS.