Tumor-targeting of viral vectors for cancer gene therapy by using antibodies or their genes against tumor-associated antigens

被引：0

作者：

Kuroki, M ^{[1
]}

Shibaguchi, H

Hachimine, K

Kinugasa, T

Badran, A

机构：

[1] Fukuoka Univ, Sch Med, Dept Biochem, Jonan Ku, Fukuoka 8140180, Japan

[2] Fukuoka Univ, Ctr Mol Oncol, Jonan Ku, Fukuoka 8140180, Japan

来源：

ANTICANCER RESEARCH | 2004年 / 24卷 / 5C期

关键词：

cancer gene therapy; viral vector; tumor; targeting; tumor-associated antigen;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Gene therapy is a promising modality for the treatment of malignant tumors for which conventional therapies are often inadequate. Various therapeutic genes have shown Promise for tumor cell killing. However, successful gene therapy depends on the development of efficient and targeted gene transfer vectors. The aim of this review is to summarize the tumor-targeting viral vectors for cancer gene therapy by utilizing antibodies or genes against tumor-associated antigens.

引用

页码：3373 / 3377

页数：5

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