Monodisperse core-shell particles composed of magnetite and dye-functionalized mesoporous silica

被引：2
|
作者：
Eurov, D. A. [1 ,2 ]
Kurdyukov, D. A. [1 ]
Medvedev, A. V. [1 ]
Kirilenko, D. A. [1 ]
Yakovlev, D. R. [3 ]
Golubev, V. G. [1 ]
机构：
[1] Ioffe Inst, St Petersburg 194021, Russia
[2] ITMO Univ, St Petersburg 199034, Russia
[3] Tech Univ Dortmund, Expt Phys 2, Dortmund, Germany
来源：
TECHNICAL PHYSICS LETTERS | 2017年 / 43卷 / 08期
基金：
俄罗斯基础研究基金会;
关键词：
IRON-OXIDE NANOPARTICLES; MRI CONTRAST AGENTS; STRATEGIES;
D O I：
10.1134/S1063785017080065
中图分类号：
O59 [应用物理学];
学科分类号：
摘要：
Hybrid particles with a core-shell structure have been obtained in the form of monodisperse spherical mesoporous silica particles filled with magnetite and covered with a mesoporous silica shell functionalized with a luminescent dye. The particles have a small root-mean-square size deviation (at most 10%), possess a specific surface area and specific pore volume of up to 250 m(2)/g and 0.15 cm(3)/g, respectively, and exhibit visible luminescence peaked at a wavelength of 530 nm. The particles can be used in diagnostics of cancerous diseases, serving simultaneously for therapeutic (magnetic hyperthermia and targeted drug delivery) and diagnostic (contrast agent for magnetic-resonance tomography and luminescent marker) purposes.
引用
收藏
页码：716 / 719
页数：4
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