Non-Cross-Linked Polystyrene Supported Cyclosulfamide as a New Chiral Auxiliary for Asymmetric Aldol Reactions

被引：7
|
作者：
Lu, Taotao
Lu, Cuifen
Nie, Junqi
Chen, Zuxing
Yang, Guichun
机构：
[1] Hubei Univ, Hubei Collaborat Innovat, Ctr Adv Organochem Mat, Wuhan 430062, Hubei, Peoples R China
[2] Hubei Univ, Minist Educ, Key Lab Synth & Applicat Organ Funct Mol, Wuhan 430062, Hubei, Peoples R China
来源：
CURRENT ORGANIC SYNTHESIS | 2015年 / 12卷 / 01期
关键词：
Asymmetric aldol reactions; chiral auxiliary; cyclosulfamide; non-cross-linked polystyrene; supported; OXAZOLIDIN-2-ONE;
D O I：
10.2174/1570179411666140530211735
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of a new non-cross-linked polystyrene supported cyclosulfamide chiral auxiliary is described. Asymmetric aldol reactions using this auxiliary proceeded with good yields and excellent stereoselectivities, which were comparable with those observed by using non-supported cyclosulfamide chiral auxiliary. Furthermore, recovery and recycling of this polymer supported chiral auxiliary have been successfully achieved without appreciable reduction in the yield or stereoselectivity.
引用
收藏
页码：61 / 66
页数：6
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