Synthesis and resolution of benzylisopropylphenylphosphine a monodentate P-chiral ligand

被引：35

作者：

Albert, J ^{[1
]}

Bosque, R ^{[1
]}

Cadena, JM ^{[1
]}

Granell, JR ^{[1
]}

Muller, G ^{[1
]}

Ordinas, JI ^{[1
]}

机构：

[1] Univ Barcelona, Dept Quim Inorgan, E-08028 Barcelona, Spain

来源：

TETRAHEDRON-ASYMMETRY | 2000年 / 11卷 / 16期

关键词：

D O I：

10.1016/S0957-4166(00)00300-1

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The synthesis of benzylisopropylphenylphosphine by reaction between the benzylphenylphosphide anion and isopropyl chloride and its subsequent resolution by means of an optically active palladium metallacycle is reported. The synthesis of the organometallic complex [Pd(eta(3)-2-MeC3H4)Cl((PBnPrPh)-Pr-i)] is also described, as well as the assignment of the absolute configuration of the coordinated phosphine by mono- and bidimensional proton NMR spectra, using the homochiral palladacycle as a reference point. In order to estimate the height of the energy barrier corresponding to the rotation of the phosphine ligand around the Pd-P bond, several calculations were performed at the semiempirical PM3(tm) level. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：3335 / 3343

页数：9

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