Dendritic cells as natural adjuvants and modulators of immune response in cancer immunotherapy

被引:0
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作者
Alli, RS [1 ]
Khar, A [1 ]
机构
[1] Ctr Cellular & Mol Biol, Hyderabad 500007, Andhra Pradesh, India
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中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Dendritic cells (DCs) are potent antigen presenting cells. Mature DCs activate antigen specific naive T cells, B cells and NK cells. Under certain conditions, DCs even silence T cell immune responses in vivo, thus, modulating the immune response. This special function of DCs could be exploited in the treatment of cancer, autoimmune disorder and chronic viral infections.
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页码:363 / 367
页数:5
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