Estrogenic and Anti-Alzheimer's studies of Zingiber officinalis as well as Amomum subulatum Roxb.: the success story of dry techniques

被引：14

作者：

Kumar, Ashwani ^{[1
]}

Goyal, Ruchika ^{[1
]}

Kumar, Sunil ^{[1
]}

Jain, Sandeep ^{[1
]}

Jain, Neelam ^{[2
]}

Kumar, Parvin ^{[3
]}

机构：

[1] Guru Jambheshwar Univ Sci & Technol, Dept Pharmaceut Sci, Drug Discovery & Res Lab, Hisar 125001, Haryana, India

[2] BPS Women Univ, Sch Pharmaceut Educ & Res, Khanpur Kalan, Sonepat, India

[3] Kurukshetra Univ, Dept Chem, Kurukshetra 132119, Haryana, India

来源：

MEDICINAL CHEMISTRY RESEARCH | 2015年 / 24卷 / 03期

关键词：

Ginger; Cardamom; Estrogen receptor; Anti-alzheimer's activity; Docking; DOCKING;

D O I：

10.1007/s00044-014-1166-y

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The extracts of ginger and cardamom were chosen for studies on estrogen receptors and Alzheimer's disease on the basis of various in silico studies of their constituents. Estrogenic effect was evaluated by uterine weight method while effect on learning and memory was studied using elevated plus maze method. Cardamom extract showed better estrogenic effect as compared to ginger. Reverse trend was observed in case of anti-alzheimer's activity. Both extracts exhibited considerable improvement in learning and memory.

引用

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页码：1089 / 1097

页数：9

共 2 条

[1] Estrogenic and Anti-Alzheimer’s studies of Zingiber officinalis as well as Amomum subulatum Roxb.: the success story of dry techniques
Ashwani Kumar
Ruchika Goyal
Sunil Kumar
Sandeep Jain
Neelam Jain
Parvin Kumar
Medicinal Chemistry Research, 2015, 24 : 1089 - 1097
[2] UPLC-ESI–MS/MS phytochemical profile, in vitro, in vivo, and in silico anti-Alzheimer’s activity assessment of Pithecellobium dulce (Roxb.) Benth. leaves
Alaa A. Elhewehy
Ahlam M. El-fishawy
Ahmed A. El-Rashedy
Ahmed M. Fayez
Marwa A. A. Fayed
Engy Mohsen
Future Journal of Pharmaceutical Sciences, 11 (1)

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