Focal Takotsubo Cardiomyopathy With High-Dose Interleukin-2 Therapy for Malignant Melanoma

被引:10
|
作者
Damodaran, Senthil [1 ]
Mrozek, Ewa [1 ]
Liebner, David [1 ]
Kendra, Kari [1 ]
机构
[1] Ohio State Univ, Wexner Med Ctr, Div Med Oncol, Columbus, OH 43210 USA
关键词
REVERSIBLE CARDIOMYOPATHY; METASTATIC MELANOMA;
D O I
10.6004/jnccn.2014.0168
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
High-dose interleukin-2 (IL-2) is an available treatment option for patients with metastatic melanoma or renal cell carcinoma, and is associated with sustained complete and partial responses in a subset of patients. IL-2, however, is not devoid of toxicities, most of which involve the cardiovascular system and manifest as hypotension, arrhythmias, and cardiomyopathy. This report describes an unusual presentation of takotsubo cardiomyopathy in a postmenopausal woman receiving high-dose IL-2 for metastatic melanoma.
引用
收藏
页码:1666 / 1670
页数:5
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