Amiodarone-induced optic neuropathy: A rare side effect

被引：2

作者：

Arcani, R. ^{[1
]}

Pellerey, M. ^{[1
]}

Rouby, F. ^{[2
]}

Gobin, N. ^{[1
]}

Scapin, J. ^{[1
]}

Chagny, M. ^{[3
]}

Arnould, T. ^{[3
]}

Ambrosi, P. ^{[1
]}

Gayet, S. ^{[1
]}

Micallef, J. ^{[2
]}

Villani, P. ^{[1
]}

Daumas, A. ^{[1
]}

机构：

[1] Aix Marseille Univ, Hop Timone, AP HM, Serv Med Interne Geriatric & Therapeut, 264 Rue St Pierre, F-13385 Marseille, France

[2] Aix Marseille Univ, Hop Timone, AP HM, Serv Ophtalmol, 264 Rue St Pierre, F-13385 Marseille, France

[3] Aix Marseille Univ, Hop Timone,Marseille Provence Corse, AP HM,Ctr Reg Pharmacovigilance, Serv Pharmacol Clin & Pharmacovigilance, 264 Rue St Pierre, F-13385 Marseille, France

来源：

REVUE DE MEDECINE INTERNE | 2019年 / 40卷 / 12期

关键词：

Amiodarone; Papillary disease; Optic neuropathy; Toxicity;

D O I：

10.1016/j.revmed.2019.09.001

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Introduction. - The diagnosis of bilateral papilledema implies emergency medical care to look for intracranial hypertension and arteritic ischemic neuropathy. However, other causes must also be mentioned, including drugs. Too often underrated because of their usual benignity, drug side ophthalmological effects can be severe and are typically bilateral. Case report. - An 80-year-old woman was hospitalized for bilateral papilledema, predominantly in the left eye, with lowered visual acuity. After ruling out intracranial hypertension, arteritic ischemic optic neuropathy, non-arteritic, and inflammatory bilateral papilledema, the diagnosis was toxic optic neuropathy. Conclusion. - Bilateral edematous optic neuropathy is a known side effect of amiodarone, uncommon but to be known because of the large number of patients benefiting from this treatment. (C) 2019 Societe Nationale Francaise de Medecine Interne (SNFMI). Published by Elsevier Masson SAS. All rights reserved.

引用

页码：826 / 830

页数：5

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