Acute kidney injury secondary to severe delayed haemolysis in intravenous artesunate use for severe malaria

被引：4
|
作者：
Leong, Kai Wen [1 ]
Singh, Kasha P. [2 ,3 ]
Leder, Karin [2 ,4 ]
Tong, Steven Y. C. [2 ,3 ]
机构：
[1] Royal Melbourne Hosp, Victorian Infect Dis Serv, Melbourne, Vic, Australia
[2] Royal Melbourne Hosp, Victorian Infect Dis Serv, Peter Doherty Inst Infect & Immun, Melbourne, Vic, Australia
[3] Univ Melbourne, Peter Doherty Inst Infect & Immun, Dept Infect Dis, Melbourne, Vic, Australia
[4] Monash Univ, Sch Publ Hlth & Prevent Med, Melbourne, Vic, Australia
来源：
BMJ CASE REPORTS | 2021年 / 14卷 / 01期
关键词：
drugs: infectious diseases; tropical medicine (infectious disease); acute renal failure; haematology (incl blood transfusion);
D O I：
10.1136/bcr-2020-237501
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The use of artemisinin derivatives has been recommended by the WHO guidelines in malaria treatment largely due to its rapid parasite clearance and safety profile. This case report details the development of delayed haemolysis and subsequent severe acute kidney injury (AKI) 13 days after commencing intravenous artesunate treatment for malaria in an Australian returned traveller. Delayed haemolysis may be an under-recognised complication following artesunate use and if severe, can be complicated by AKI. Therefore, close patient follow-up following treatment is required to ensure prompt recognition of this phenomenon.
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页数：3
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